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A historical view Of Peyronie’s Disease

a group of men standing on top of a boat

Peyronie’s Disease is a condition that affects men, characterized by the development of fibrous plaques in the penile tissue, which can cause curvature and pain during erections. The condition is named after Francois Gigot de la Peyronie, a French surgeon who first described it in 1743. Since then, Peyronie’s Disease has been the subject of much study and speculation, with a rich history of medical advances and social stigma.

Early descriptions of Peyronie’s Disease

Francois Gigot de la Peyronie’s original description of the condition was based on a series of cases he had observed in his own practice. He noted that men with PD typically had a thickening of the penile tissue, which caused a curvature during erection. This curvature often made sexual intercourse difficult or impossible. Peyronie also noted that the condition tended to occur in older men, and speculated that it might be related to gout or rheumatism.

Following Peyronie’s initial description of the condition, several other physicians began to report cases of what they called “induratio penis plastica,” or plastic induration of the penis. In the 19th and early 20th centuries, the condition was still poorly understood, and various theories were proposed to explain its cause. Some physicians believed that Peyronie’s Disease was a result of inflammation or trauma to the penis, while others suggested that it might be caused by a bacterial or viral infection.

Medical advances in the 20th century

It was not until the mid-20th century that significant progress was made in understanding Peyronie’s Disease. In the 1950s, a urologist named Dr. Ralph V. Clayman published a landmark paper in which he described what causes PD in men. He proposed that the condition was caused by the deposition of collagen in the penile tissue. This theory was later confirmed by studies showing that the fibrous plaques associated with Peyronie’s Disease are composed mainly of collagen.

In the 1970s, a new treatment for Peyronie’s Disease was developed that involved injecting a drug called verapamil directly into the fibrous plaques. Verapamil is a calcium channel blocker that has been used for many years to treat high blood pressure and other conditions. Studies showed that when verapamil was injected into the fibrous plaques, it could help to break down the collagen and reduce the curvature of the penis.

Other Peyronie’s disease treatments have been developed in the decades since, including surgery to remove the fibrous plaques or implant a prosthesis to straighten the penis. However, these treatments can be expensive and carry risks of their own.

In recent times, non-invasive treatments like shockwave therapy and EMTT therapy are being used to treat PD. Shockwave therapy for Peyronie’s disease uses high intensity sound waves and EMTT therapy uses electro-magnetic energy to remove the plaques in penis. According to Shockwave Clinics Ltd, which is a specialized men’s health clinic located in London, shockwave therapy is very effective in treating PD in men. The clinic also offers other non-invasive Peyronie’s disease treatments such as, Tesla Chair and NanoVi.

Social stigma and psychological impact

Peyronie’s Disease can be a difficult condition for men to cope with, both physically and emotionally. The curvature and pain associated with the condition can make sexual intercourse difficult or impossible, which can lead to feelings of frustration, embarrassment, and shame. Men with Peyronie’s Disease may also worry about how their condition will be perceived by sexual partners, and may be reluctant to seek medical treatment for fear of being judged or stigmatized.

Historically, there has been a great deal of social stigma associated with Peyronie’s Disease and other conditions that affect male sexual function. Men with erectile dysfunction, premature ejaculation, or other sexual problems have often been seen as weak or inadequate, and have been reluctant to seek help as a result. However, in recent years, there has been a growing recognition of the psychological impact that Peyronie’s Disease and other sexual problems can have on men, and there is increasing awareness of the need for compassionate and effective medical treatment.


Peyronie’s Disease has a long and complex history, with many advances in understanding and treating the condition being made in recent years. While it was once poorly understood and stigmatized, we now have a much clearer picture of what causes PD in a man, and there are a range of treatments available to help alleviate its symptoms.

However, it is important to remember that Peyronie’s Disease can still have a significant psychological impact on men who suffer from it. The stigma surrounding male sexual function can make it difficult for men to seek help, and it is important for healthcare providers to offer compassionate and understanding care to men with PD.

Looking forward, ongoing research into the causes and treatment options for Peyronie’s disease will likely continue to improve our understanding of this complex condition. As we continue to learn more about how the fibrous plaques form and progress, it may be possible to develop new Peyronie’s disease treatments that can more effectively break down the collagen and alleviate the symptoms of the condition.

In the meantime, it is important for men who are experiencing symptoms of Peyronie’s Disease to seek medical attention and explore the range of treatment options that are available. With the right care and Peyronies Forum support, men with PD can continue to lead healthy and fulfilling lives, free from the pain and limitations that the condition can cause.

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